Everything Is Poison
by Joy McCullough
High School    Dutton    304 pp.
1/25    9780593855874    $19.99
e-book ed.  9780593855898    $10.99

In 1650s Rome, Carmela’s mother, Giulia Tofana, runs an apothecary. At sixteen, Carmela is finally allowed to begin training to become an apothecary herself. She learns what goes into healing remedies—familiar herbs such as lavender, rosemary, and pennyroyal, but also urine, dog feces, dried menstrual blood, and more. What surprises her most is Giulia’s willingness to help all who come to her. “There are so many who have no one else to turn to,” Giulia says. “That is the daily work we are here for. Giving women a choice over what happens in their bodies,” whether it be rheumatism, rashes, birth, dangerous pregnancies, or life-threatening marriages. When an abused wife fails to administer the toxic “Acqua Tofana” to her murderous husband properly, Giulia must flee for her life, leaving Carmela to carry on the work. This is an unforgettable novel of courage, chemistry, and female solidarity in a casually violent, misogynistic world—in short, in many ways, a topical story. McCullough enfolds a catalog of women’s hardships and mutual support warmly and dramatically into the immersive tale of Carmela’s growth from dependency and childhood grievances to confident generosity, skill, and compassion. Occasional verse interludes emphasize the pervasiveness of Giulia’s clients’ difficulties.

From the March/April 2025 issue of The Horn Book Magazine.